The average train between Pisa and Ascoli Piceno takes 7h 33m and the fastest train takes 5h 32m. The train service runs several times per day from Pisa to Ascoli Piceno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Pisa and Ascoli Piceno. The earliest departure is at 4:15 AM at night, and the last departure from Pisa is at 5:32 PM which arrives into Ascoli Piceno at 7:53 AM. All services require a transfer at Firenze S.M.N. and take an average of 7h 33m. The schedules shown below are for the next available departures.



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9h 27m • 3 changes


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5h 35m • 3 changes


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6h 15m • 3 changesWant to know about travelling from Pisa to Ascoli Piceno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Ascoli Piceno. However, there are services departing from Pisa station and arriving at Ascoli Piceno station via Firenze S.M.N.. The journey, including transfers, takes approximately 7h 33m.
Pisa to Ascoli Piceno train services, operated by Trenitalia, depart from Pisa Centrale station.
Pisa to Ascoli Piceno train services, operated by Trenitalia, arrive at San Benedetto Tronto station.
Book your Pisa to Ascoli Piceno train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Pisa and Ascoli Piceno is 273.7 km. The road distance is 490 km.
You can take a train from Pisa Centrale to Ascoli Piceno via Firenze S.M.N., Bologna Centrale, and San Benedetto Tronto in around 6h 35m.