The average train between Pisa and Avezzano takes 9h 18m and the fastest train takes 5h 57m. The train service runs several times per day from Pisa to Avezzano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Pisa and Avezzano. The earliest departure is at 7:33 AM in the morning, and the last departure from Pisa is at 8:38 PM which arrives into Avezzano at 9:15 AM. All services require a transfer, and take on average 9h 18m. The schedules shown below are for the next available departures.

6h 17m • 1 change

8h 31m • 1 change
Arrives next day

13h 14m • 1 change

6h 17m • 1 change

8h 31m • 1 change
Arrives next day

13h 14m • 1 change

6h 17m • 1 change

8h 31m • 1 change
Arrives next day

13h 14m • 1 change
Want to know about travelling from Pisa to Avezzano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Avezzano. However, there are services departing from Pisa station and arriving at Avezzano station via Roma Tiburtina. The journey, including transfers, takes approximately 9h 18m.
Pisa to Avezzano train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.
Pisa to Avezzano train services, operated by Trenitalia Frecce, arrive at Avezzano station.
Book your Pisa to Avezzano train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Pisa and Avezzano is 309.1 km. The road distance is 436 km.
You can take a train from Pisa Centrale to Avezzano via Roma Tiburtina in around 4h 24m.