The average train between Pisa and Brindisi takes 14h 20m and the fastest train takes 11h 5m. The train service runs several times per day from Pisa to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Pisa and Brindisi. The earliest departure is at 7:33 AM in the morning, and the last departure from Pisa is at 8:38 PM which arrives into Brindisi at 1:57 PM. All services require a transfer at Roma Tiburtina and take an average of 14h 20m. The schedules shown below are for the next available departures.
Want to know about travelling from Pisa to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Brindisi. However, there are services departing from Pisa station and arriving at Brindisi station via Roma Tiburtina. The journey, including transfers, takes approximately 14h 20m.
Pisa to Brindisi train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.
Pisa to Brindisi train services, operated by Trenitalia Frecce, arrive at Brindisi station.
Book your Pisa to Brindisi train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Pisa and Brindisi is 708.4 km. The road distance is 924 km.
You can take a train from Pisa Centrale to Brindisi via Roma Tiburtina and Roma Termini in around 8h 46m.