The average train between Pisa and Colosseum takes 3h 51m and the fastest train takes 2h 43m. There is a train service every few hours from Pisa to Colosseum. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Pisa and Colosseum. The earliest departure is at 5:40 AM in the morning, and the last departure from Pisa is at 8:38 PM which arrives into Colosseum at 5:49 AM. All services require a transfer at Rome Termini and take an average of 3h 51m. The schedules shown below are for the next available departures.

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3h 28m • 1 changeWant to know about travelling from Pisa to Colosseum? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Colosseum. However, there are services departing from Pisa station and arriving at Colosseum station via Roma Termini. The journey, including transfers, takes approximately 3h 51m.
Pisa to Colosseum train services, operated by Trenitalia, depart from Pisa Centrale station.
Pisa to Colosseum train services, operated by Trenitalia, arrive at Roma Termini station.
The distance between Pisa and Colosseum is 264.4 km. The road distance is 333 km.
Trenitalia Frecce operates a train from Pisa Centrale to Roma Termini every 4 hours. Tickets cost €45–95 and the journey takes 2h 56m. Two other operators also service this route.