Pisa to Domodossola Trains

Trip Overview

The average train between Pisa and Domodossola takes 6h 47m and the fastest train takes 5h 34m. The train service runs several times per day from Pisa to Domodossola. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 47m
Duration: 503 km
Distance: €112
Average price: 5 times a day
Frequency

Train via Bologna

best

Take the train from Pisa Centrale to Firenze S.M.N.train Re
Take the train from Firenze S.M.N. to Bologna Centraletrain Fr
Take the train from Bologna centrale to Milano Centraletrain
Take the train from Milano Centrale to Domodossolatrain Ec

6h 13m

€74–203

Pisa to Domodossola train times

Trains run 5 times a day between Pisa and Domodossola. The earliest departure is at 6:54 AM in the morning, and the last departure from Pisa is at 7:54 PM which arrives into Domodossola at 8:43 AM. All services require a transfer at Firenze S.M.N. and take an average of 6h 47m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

6:54 AM → 12:43 PM
5h 49m • 3 changes
9:09 AM → 2:43 PM
5h 34m • 3 changes
10:54 AM → 4:43 PM
5h 49m • 3 changes
1:09 PM → 6:43 PM
5h 34m • 3 changes
Show more

Departing Monday, November 9, 2026

11:09 AM → 4:43 PM
5h 34m • 3 changes
1:09 PM → 6:43 PM
5h 34m • 3 changes
1:54 PM → 7:43 PM
5h 49m • 3 changes
3:09 PM → 8:43 PM
5h 34m • 3 changes
Show more

Departing Tuesday, November 10, 2026

11:09 AM → 4:43 PM
5h 34m • 3 changes
1:09 PM → 6:43 PM
5h 34m • 3 changes
1:54 PM → 7:43 PM
5h 49m • 3 changes
3:09 PM → 8:43 PM
5h 34m • 3 changes
Show more

Departing Wednesday, November 11, 2026

11:09 AM → 4:43 PM
5h 34m • 3 changes
1:09 PM → 6:43 PM
5h 34m • 3 changes
1:54 PM → 7:43 PM
5h 49m • 3 changes
3:09 PM → 8:43 PM
5h 34m • 3 changes
Show more

Departing Thursday, November 12, 2026

11:09 AM → 4:43 PM
5h 34m • 3 changes
1:09 PM → 6:43 PM
5h 34m • 3 changes
1:54 PM → 7:43 PM
5h 49m • 3 changes
3:09 PM → 8:43 PM
5h 34m • 3 changes
Show more

Departing Friday, November 13, 2026

11:09 AM → 4:43 PM
5h 34m • 3 changes
1:09 PM → 6:43 PM
5h 34m • 3 changes
1:54 PM → 7:43 PM
5h 49m • 3 changes
3:09 PM → 8:43 PM
5h 34m • 3 changes
Show more

Departing Saturday, November 14, 2026

6:54 AM → 12:43 PM
5h 49m • 3 changes
9:09 AM → 2:43 PM
5h 34m • 3 changes
11:09 AM → 4:43 PM
5h 34m • 3 changes
1:09 PM → 6:43 PM
5h 34m • 3 changes
Show more

Frequently asked questions

Want to know about travelling from Pisa to Domodossola? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.