The average train between Pisa and Lazio takes 5h 47m and the fastest train takes 2h 46m. The train service runs several times per day from Pisa to Lazio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Pisa and Lazio. The earliest departure is at 7:33 AM in the morning, and the last departure from Pisa is at 8:38 PM which arrives into Lazio at 9:19 AM. All services require a transfer, and take on average 5h 47m. The schedules shown below are for the next available departures.

3h 27m • 1 change

2h 55m • 1 change
Arrives next day

12h 41m • 1 change

3h 27m • 1 change

2h 55m • 1 change
Arrives next day

12h 41m • 1 change

3h 27m • 1 change

2h 55m • 1 change
Arrives next day

12h 41m • 1 change

3h 27m • 1 change

2h 55m • 1 change
Arrives next day

12h 41m • 1 change
Want to know about travelling from Pisa to Lazio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Lazio. However, there are services departing from Pisa station and arriving at Lazio station via Roma Tiburtina. The journey, including transfers, takes approximately 5h 47m.
Pisa to Lazio train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.
Pisa to Lazio train services, operated by Trenitalia Frecce, arrive at Roma Tiburtina station.
Book your Pisa to Lazio train tickets online with Trenitalia Frecce and ItaloTreno.
The distance between Pisa and Lazio is 272 km. The road distance is 336 km.
Trenitalia Frecce operates a train from Pisa Centrale to Roma Tiburtina 5 times a day. Tickets cost €50–100 and the journey takes 2h 9m.