The average train between Pisa and Milano Centrale Station takes 3h 39m and the fastest train takes 3h 21m. There is a train service every few hours from Pisa to Milano Centrale Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Pisa and Milano Centrale Station. The earliest departure is at 5:19 AM in the morning, and the last departure from Pisa is at 8:32 PM which arrives into Milano Centrale Station at 12:05 AM. All services require a transfer, and take on average 3h 39m. The schedules shown below are for the next available departures.

4h 6m • 1 change

3h 51m • 1 change

3h 46m • 1 change

3h 48m • 1 change

3h 46m • 1 change

3h 31m • 1 change

3h 21m • 1 change

3h 33m • 1 change

3h 46m • 1 change

3h 31m • 1 change

3h 21m • 1 change

3h 33m • 1 change

3h 46m • 1 change

3h 31m • 1 change

3h 21m • 1 change

3h 33m • 1 change
Want to know about travelling from Pisa to Milano Centrale Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Milano Centrale Station. However, there are services departing from Pisa station and arriving at Milano Centrale Station station via Firenze S.M.N.. The journey, including transfers, takes approximately 3h 39m.
Pisa to Milano Centrale Station train services, operated by Trenitalia, depart from Pisa Centrale station.
Pisa to Milano Centrale Station train services, operated by Trenitalia, arrive at Milano Centrale station.
Book your Pisa to Milano Centrale Station train tickets online with Trenitalia and Trenitalia Frecce.
The distance between Pisa and Milano Centrale Station is 219.4 km. The road distance is 382 km.
You can take a train from Pisa Centrale to Milano Centrale via Firenze S.M.N. in around 3h 35m.