The average train between Pisa and Piazza del Duomo takes 3h 26m and the fastest train takes 3h 10m. There is a train service every few hours from Pisa to Piazza del Duomo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Pisa and Piazza del Duomo. The earliest departure is at 5:19 AM in the morning, and the last departure from Pisa is at 8:32 PM which arrives into Piazza del Duomo at 11:55 PM. All services require a transfer at Firenze S.M.N. and take an average of 3h 26m. The schedules shown below are for the next available departures.


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3h 10m • 2 changesWant to know about travelling from Pisa to Piazza del Duomo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Piazza del Duomo. However, there are services departing from Pisa station and arriving at Piazza del Duomo station via Firenze S.M.N.. The journey, including transfers, takes approximately 3h 26m.
Pisa to Piazza del Duomo train services, operated by Trenitalia, depart from Pisa Centrale station.
Pisa to Piazza del Duomo train services, operated by Trenitalia, arrive at Milano Rogoredo station.
The distance between Pisa and Piazza del Duomo is 217.6 km. The road distance is 380 km.
You can take a train from Pisa Centrale to Piazza del Duomo via Firenze S.M.N., Milano Rogoredo, Rogoredo Fs, and Duomo M3 in around 3h 39m.