The average train between Pisa and Roma Ostiense takes 4h 53m and the fastest train takes 2h 56m. The train service runs several times per day from Pisa to Roma Ostiense. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Pisa and Roma Ostiense. The earliest departure is at 6:12 AM in the morning, and the last departure from Pisa is at 8:38 PM which arrives into Roma Ostiense at 5:14 AM. All services require a transfer, and take on average 4h 53m. The schedules shown below are for the next available departures.

2h 56m • 1 change

2h 59m • 1 change
Arrives next day

8h 36m • 1 change

3h 41m • 1 change

2h 59m • 1 change
Arrives next day

8h 36m • 1 change

2h 56m • 1 change

2h 59m • 1 change
Arrives next day

8h 36m • 1 change

2h 56m • 1 change

2h 59m • 1 change
Arrives next day

8h 36m • 1 change
Want to know about travelling from Pisa to Roma Ostiense? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Roma Ostiense. However, there are services departing from Pisa station and arriving at Roma Ostiense station via Roma Tiburtina. The journey, including transfers, takes approximately 4h 53m.
Pisa to Roma Ostiense train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.
Pisa to Roma Ostiense train services, operated by Trenitalia Frecce, arrive at Roma Tiburtina station.
Book your Pisa to Roma Ostiense train tickets online with Trenitalia Frecce, Trenitalia and Trenitalia Intercity.
The distance between Pisa and Roma Ostiense is 265.5 km. The road distance is 339 km.
Trenitalia Frecce operates a train from Pisa Centrale to Roma Tiburtina 5 times a day. Tickets cost €50–100 and the journey takes 2h 9m. Trenitalia Intercity also services this route 4 times a week.