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Pisa to Santander trains

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Trip Overview

The train between Pisa and Santander takes 2d 4h. The train runs, on average, 5 times per week from Pisa to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 4h
Duration
2,161 km
Distance
€340
Average price
5 times a week
Frequency

Pisa to Santander train times

Trains run 5 times a week between Pisa and Santander. The service departs Pisa at 7:03 PM in the evening, which arrives into Santander at 23:12:00. All services require a transfer at Ventimiglia and take an average of 2d 4h. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

  •  → 

    Arrives +2 days

    Trenitalia IntercityZOU!TGV inOuiRenfe ViajerosRenfe CercaniasRenfe Viajeros2d 4h • 5 changes

Departing Monday, November 2, 2026

  •  → 

    Arrives +2 days

    Trenitalia IntercityZOU!TGV inOuiRenfe ViajerosRenfe CercaniasRenfe Viajeros2d 4h • 5 changes

Departing Tuesday, November 3, 2026

  •  → 

    Arrives +2 days

    Trenitalia IntercityZOU!TGV inOuiRenfe ViajerosRenfe CercaniasRenfe Viajeros2d 4h • 5 changes

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    Trenitalia IntercityZOU!TGV inOuiRenfe ViajerosRenfe CercaniasRenfe Viajeros2d 4h • 5 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    Trenitalia IntercityZOU!TGV inOuiRenfe ViajerosRenfe CercaniasRenfe Viajeros2d 4h • 5 changes

Frequently asked questions

Want to know about travelling from Pisa to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pisa to Santander.ExpandLaunch map view
  • Distance: 2,161.3 km
  • Duration: 2d 4h

What companies run services between Pisa, Italy and Santander, Spain?

You can take a train from Pisa Centrale to Santander via Ventimiglia, Nice Ville, Marseille St Charles, Madrid-Puerta De Atocha-Almudena Grandes, Madrid-Atocha Cercanías, and Madrid Chamartín in around 23h 48m.

Operators