The average train between Pisa and Sezze takes 6h 17m and the fastest train takes 4h 10m. The train service runs several times per day from Pisa to Sezze. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Pisa and Sezze. The earliest departure is at 7:33 AM in the morning, and the last departure from Pisa is at 8:38 PM which arrives into Sezze at 6:13 AM. All services require a transfer at Roma Tiburtina and take an average of 6h 17m. The schedules shown below are for the next available departures.


5h 4m • 2 changes


4h 10m • 2 changes
Arrives next day


9h 10m • 2 changes


5h 4m • 2 changes


4h 10m • 2 changes
Arrives next day


9h 10m • 2 changes


5h 4m • 2 changes


4h 10m • 2 changes
Arrives next day


9h 10m • 2 changes


5h 4m • 2 changes


4h 10m • 2 changes
Arrives next day


9h 10m • 2 changes
Want to know about travelling from Pisa to Sezze? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa to Sezze. However, there are services departing from Pisa station and arriving at Sezze station via Roma Tiburtina. The journey, including transfers, takes approximately 6h 17m.
Pisa to Sezze train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.
Pisa to Sezze train services, operated by Trenitalia Frecce, arrive at Sezze Romano station.
Book your Pisa to Sezze train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Pisa and Sezze is 328 km. The road distance is 406 km.
You can take a train from Pisa Centrale to Sezze Romano via Roma Tiburtina and Roma Termini in around 3h 27m.