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Pittsburgh to Florence trains

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Trip Overview

The train between Pittsburgh and Florence takes 21h 45m. There is at least one train per day from Pittsburgh to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 45m
Duration
698 mi
Distance
$449
Average price
Once daily
Frequency

Pittsburgh to Florence train times

Trains run once daily between Pittsburgh and Florence. The service departs Pittsburgh at 5:25 AM in the morning, which arrives into Florence at 03:10:00. All services require a transfer, and take on average 21h 45m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    AmtrakAmtrak21h 45m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    AmtrakAmtrak21h 45m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    AmtrakAmtrak21h 45m • 1 change

Departing Saturday, November 14, 2026

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    Arrives next day

    AmtrakAmtrak21h 45m • 1 change

Departing Sunday, November 15, 2026

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    Arrives next day

    AmtrakAmtrak21h 45m • 1 change

Departing Monday, November 16, 2026

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    Arrives next day

    AmtrakAmtrak21h 45m • 1 change

Frequently asked questions

Want to know about travelling from Pittsburgh to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pittsburgh to Florence.ExpandLaunch map view
  • Distance: 698.4 mi
  • Duration: 21h 45m

What companies run services between Pittsburgh, PA, USA and Florence, SC, USA?

You can take a train from Pittsburgh Amtrak Station to Florence Station via Richmond Staples Mill Road Amtrak Station in around 17h 14m.

Operators