The average train between Plymouth and Uxbridge takes 3h 50m and the fastest train takes 3h 31m. There is a train service every few hours from Plymouth to Uxbridge. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Plymouth and Uxbridge. The earliest departure is at 4:54 AM at night, and the last departure from Plymouth is at 11:56 PM which arrives into Uxbridge at 5:08 AM. All services require a transfer, and take on average 3h 50m. The schedules shown below are for the next available departures.

3h 51m • 1 change

3h 52m • 1 change

4h 5m • 1 change

3h 44m • 1 change

3h 51m • 1 change

3h 52m • 1 change

4h 5m • 1 change

3h 44m • 1 change

3h 51m • 1 change

3h 52m • 1 change

4h 5m • 1 change

3h 44m • 1 change
Want to know about travelling from Plymouth to Uxbridge? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Plymouth to Uxbridge. However, there are services departing from Plymouth station and arriving at Uxbridge station via Reading. The journey, including transfers, takes approximately 3h 50m.
Plymouth to Uxbridge train services, operated by Great Western Railway (GWR), depart from Plymouth station.
Plymouth to Uxbridge train services, operated by Great Western Railway (GWR), arrive at Reading station.
Book your Plymouth to Uxbridge train tickets online with Great Western Railway (GWR) and Elizabeth Line (TfL).
The distance between Plymouth and Uxbridge is 287.8 km. The road distance is 339 km.
Great Western Railway (GWR) operates a train from Plymouth to Reading hourly. Tickets cost £80–160 and the journey takes 2h 48m.