The average train between Plzeň Region and Brno takes 5h 5m and the fastest train takes 4h 38m. There is a train service every few hours from Plzeň Region to Brno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Plzeň Region and Brno. The earliest departure is at 4:38 AM at night, and the last departure from Plzeň Region is at 9:23 PM which arrives into Brno at 2:49 AM. All services require a transfer at Plzen Hlavni Nadrazi and take an average of 5h 5m. The schedules shown below are for the next available departures.


5h 2m • 2 changes


4h 51m • 2 changes


4h 51m • 2 changes


4h 38m • 2 changes


5h 2m • 2 changes


4h 51m • 2 changes


4h 51m • 2 changes


4h 38m • 2 changes


5h 2m • 2 changes


4h 51m • 2 changes


4h 51m • 2 changes


4h 38m • 2 changes


5h 2m • 2 changes


4h 51m • 2 changes


4h 51m • 2 changes


4h 38m • 2 changes
Want to know about travelling from Plzeň Region to Brno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Plzeň Region to Brno. However, there are services departing from Plzeň Region station and arriving at Brno station via Praha Hlavni Nadrazi. The journey, including transfers, takes approximately 5h 5m.
Plzeň Region to Brno train services, operated by České dráhy (ČD), depart from Plzen Hlavni Nadrazi station.
Plzeň Region to Brno train services, operated by České dráhy (ČD), arrive at Brno Hlavni Nadrazi station.
Book your Plzeň Region to Brno train tickets online with České dráhy (ČD), RegioJet and 2 other operators.
The distance between Plzeň Region and Brno is 252.7 km. The road distance is 366 km.
You can take a train from Nyrany to Brno Hlavni Nadrazi via Plzen Hlavni Nadrazi and Praha Hlavni Nadrazi in around 4h 33m.