The average train between Plzeň Region and Karlovy Vary takes 3h 29m and the fastest train takes 2h 48m. The train service runs several times per day from Plzeň Region to Karlovy Vary. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Plzeň Region and Karlovy Vary. The earliest departure is at 6:22 AM in the morning, and the last departure from Plzeň Region is at 7:23 PM which arrives into Karlovy Vary at 10:11 PM. All services require a transfer, and take on average 3h 29m. The schedules shown below are for the next available departures.

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Want to know about travelling from Plzeň Region to Karlovy Vary? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Plzeň Region to Karlovy Vary. However, there are services departing from Plzeň Region station and arriving at Karlovy Vary station via Karlovy Vary. The journey, including transfers, takes approximately 3h 29m.
Plzeň Region to Karlovy Vary train services, operated by České dráhy (ČD), depart from Plzen-Jizni Predmesti station.
Plzeň Region to Karlovy Vary train services, operated by České dráhy (ČD), arrive at Karlovy Vary station.
Book your Plzeň Region to Karlovy Vary train tickets online with České dráhy (ČD).
The distance between Plzeň Region and Karlovy Vary is 63.7 km. The road distance is 166 km.
České dráhy (ČD) operates a train from Plzen-Jizni Predmesti to Karlovy Vary every 2 hours. Tickets cost Kč 440–700 and the journey takes 2h 3m.