The average train between Pompei and Isernia takes 3h 53m and the fastest train takes 2h 53m. The train service runs several times per day from Pompei to Isernia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Pompei and Isernia. The earliest departure is at 10:20 AM in the morning, and the last departure from Pompei is at 10:21 PM which arrives into Isernia at 2:04 PM. All services require a transfer, and take on average 3h 53m. The schedules shown below are for the next available departures.

3h 44m • 1 change

3h 3m • 1 change

3h 30m • 1 change

2h 53m • 1 change

3h 44m • 1 change

3h 3m • 1 change

3h 30m • 1 change

2h 53m • 1 change
Want to know about travelling from Pompei to Isernia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pompei to Isernia. However, there are services departing from Pompei station and arriving at Isernia station via Napoli Piazza Garibaldi. The journey, including transfers, takes approximately 3h 53m.
Pompei to Isernia train services, operated by Trenitalia, depart from Pompei station.
Pompei to Isernia train services, operated by Trenitalia, arrive at Isernia station.
Book your Pompei to Isernia train tickets online with Trenitalia.
The distance between Pompei and Isernia is 97.1 km. The road distance is 155 km.
You can take a train from Pompei to Isernia via Napoli Centrale in around 3h 47m.