Pont-Saint-Esprit to Lyon Trains

Pont-Saint-Esprit to Lyon trains

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Trip Overview

The average train between Pont-Saint-Esprit and Lyon takes 3h 23m and the fastest train takes 2h 43m. There is at least one train per day from Pont-Saint-Esprit to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 23m
Duration: 278 km
Distance: €64
Average price: Once daily
Frequency

Train

best

Take the train from Pont-Saint-Esprit to Avignon Centretrain Ter
Take the train from Avignon Tgv to Lyon Part Dieutrain Tgv

2h 20m

€37–88

Pont-Saint-Esprit to Lyon train times

Trains run once daily between Pont-Saint-Esprit and Lyon. The earliest departure is at 7:01 AM in the morning, and the last departure from Pont-Saint-Esprit is at 5:42 PM which arrives into Lyon at 10:01 PM. All services require a transfer at Avignon Centre and take an average of 3h 23m. The schedules shown below are for the next available departures.

Departing Saturday, November 14, 2026

7:01 AM → 9:54 AM
2h 53m • 2 changes
10:02 AM → 1:53 PM
3h 51m • 2 changes
11:50 AM → 3:15 PM
3h 25m • 2 changes
4:11 PM → 6:54 PM
2h 43m • 2 changes
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Departing Sunday, November 15, 2026

8:03 AM → 11:28 AM
3h 25m • 2 changes
11:50 AM → 3:20 PM
3h 30m • 2 changes
2:03 PM → 4:54 PM
2h 51m • 2 changes
5:42 PM → 9:19 PM
3h 37m • 2 changes

Frequently asked questions

Want to know about travelling from Pont-Saint-Esprit to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.