The average train between Portland and Mystic takes 5h 53m and the fastest train takes 4h 45m. The train service runs several times per day from Portland to Mystic. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Portland and Mystic. The earliest departure is at 5:18 AM in the morning, and the last departure from Portland is at 1:43 PM which arrives into Mystic at 8:06 PM. All services require a transfer at Boston and take an average of 5h 53m. The schedules shown below are for the next available departures.


5h 27m • 2 changes


7h 47m • 2 changes


4h 50m • 2 changes


6h 23m • 2 changes


5h 27m • 2 changes


7h 47m • 2 changes


4h 50m • 2 changes


6h 23m • 2 changes


5h 27m • 2 changes


7h 47m • 2 changes


4h 50m • 2 changes


6h 23m • 2 changes
Want to know about travelling from Portland to Mystic? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Portland to Mystic. However, there are services departing from Portland station and arriving at Mystic station via Boston. The journey, including transfers, takes approximately 5h 53m.
Portland to Mystic train services, operated by Amtrak, depart from Portland station.
Portland to Mystic train services, operated by Amtrak, arrive at Mystic Station.
Book your Portland to Mystic train tickets online with Amtrak and MBTA.
The distance between Portland and Mystic is 291.8 km. The road distance is 341 km.
You can take a train from Portland to Mystic Station via Boston, North Station, Back Bay, and Boston in around 5h 5m.