The average train between Potsdam and Karlsruhe takes 6h 35m and the fastest train takes 5h 44m. There is a train service every few hours from Potsdam to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Potsdam and Karlsruhe. The earliest departure is at 3:41 AM at night, and the last departure from Potsdam is at 10:41 PM which arrives into Karlsruhe at 6:59 AM. All services require a transfer, and take on average 6h 35m. The schedules shown below are for the next available departures.
Arrives next day

9h 2m • 1 change
Arrives next day

8h 17m • 1 change

6h 17m • 1 change

5h 54m • 1 change

6h 17m • 1 change

6h 7m • 1 change

6h 17m • 1 change

6h 17m • 1 change

5h 44m • 1 change

6h 17m • 1 change

6h 24m • 1 change

6h 17m • 1 change

5h 44m • 1 change

6h 17m • 1 change

6h 17m • 1 change

6h 17m • 1 change

5h 44m • 1 change

6h 17m • 1 change

6h 17m • 1 change

6h 17m • 1 change

5h 44m • 1 change

6h 17m • 1 change
Want to know about travelling from Potsdam to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Potsdam to Karlsruhe. However, there are services departing from Potsdam station and arriving at Karlsruhe station via Karlsruhe Hauptbahnhof. The journey, including transfers, takes approximately 6h 35m.
Potsdam to Karlsruhe train services, operated by S-Bahn Berlin, depart from Berlin Hbf station.
Potsdam to Karlsruhe train services, operated by S-Bahn Berlin, arrive at Karlsruhe Hauptbahnhof station.
Book your Potsdam to Karlsruhe train tickets online with S-Bahn Berlin and Deutsche Bahn Intercity (DB IC).
The distance between Potsdam and Karlsruhe is 499.6 km. The road distance is 676 km.
Deutsche Bahn Intercity (DB IC) operates a train from Berlin Hbf to Karlsruhe Hauptbahnhof every 3 hours. Tickets cost €110–550 and the journey takes 5h 16m. Österreichische Bundesbahnen also services this route 3 times a day.