The average train between Potsdam and Karlsruhe takes 6h 20m and the fastest train takes 5h 34m. There is a train service every few hours from Potsdam to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Potsdam and Karlsruhe. The earliest departure is at 3:44 AM at night, and the last departure from Potsdam is at 10:44 PM which arrives into Karlsruhe at 6:59 AM. All services require a transfer at Berlin Hbf and take an average of 6h 20m. The schedules shown below are for the next available departures.


6h 15m • 2 changes

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6h 33m • 2 changes

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5h 49m • 2 changes

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5h 49m • 2 changes

5h 34m • 2 changesWant to know about travelling from Potsdam to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Potsdam to Karlsruhe. However, there are services departing from Berlin Hbf station and arriving at Karlsruhe Hauptbahnhof station via Frankfurt station. The journey, including transfers, takes approximately 6h 20m.
Potsdam to Karlsruhe train services, operated by Deutsche Bahn Intercity (DB IC), depart from Berlin Hbf station.
Potsdam to Karlsruhe train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Karlsruhe Hauptbahnhof station.
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The distance between Potsdam and Karlsruhe is 499.6 km. The road distance is 623 km.
You can take a train from Potsdam Hbf to Karlsruhe Hauptbahnhof via Berlin Hbf and Frankfurt in around 6h 34m.