The average train between Potsdam and Karlsruhe takes 7h and the fastest train takes 6h 22m. The train service runs several times per day from Potsdam to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Potsdam and Karlsruhe. The earliest departure is at 5:36 AM in the morning, and the last departure from Potsdam is at 9:36 PM which arrives into Karlsruhe at 5:19 PM. All services require a transfer, and take on average 7h. The schedules shown below are for the next available departures.

6h 23m • 1 change

6h 23m • 1 change
Arrives next day

9h 23m • 1 change

6h 23m • 1 change

6h 23m • 1 change

6h 23m • 1 change

6h 43m • 1 change

6h 23m • 1 change

6h 23m • 1 change

6h 23m • 1 change

6h 43m • 1 change

6h 23m • 1 change

6h 23m • 1 change

6h 23m • 1 change

6h 43m • 1 change

6h 23m • 1 change

6h 23m • 1 change

6h 23m • 1 change

6h 43m • 1 change
Want to know about travelling from Potsdam to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Potsdam to Karlsruhe. However, there are services departing from Potsdam station and arriving at Karlsruhe station via Karlsruhe Hauptbahnhof. The journey, including transfers, takes approximately 7h.
Potsdam to Karlsruhe train services, operated by Deutsche Bahn Regio (DB Regional), depart from S Spandau Bhf station.
Potsdam to Karlsruhe train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Karlsruhe Hauptbahnhof station.
Book your Potsdam to Karlsruhe train tickets online with Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Potsdam and Karlsruhe is 499.6 km. The road distance is 725 km.
Deutsche Bahn Intercity (DB IC) operates a train from S Spandau Bhf to Karlsruhe Hauptbahnhof every 4 hours. Tickets cost €120–550 and the journey takes 5h 13m.