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Poughkeepsie to Cambridge trains

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Trip Overview

The average train between Poughkeepsie and Cambridge takes 6h 47m and the fastest train takes 5h 42m. The train service runs several times per day from Poughkeepsie to Cambridge. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 47m
Duration
303 mi
Distance
$197
Average price
Every 4 hours
Frequency

Train via New York (Amtrak)

best
  1. Take the train from Poughkeepsie Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
  2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train Acela
5h 47m
$160–262

Poughkeepsie to Cambridge train times

Trains run every 4 hours between Poughkeepsie and Cambridge. The earliest departure is at 7:51 AM in the morning, and the last departure from Poughkeepsie is at 8:40 PM which arrives into Cambridge at 9:58 AM. All services require a transfer, and take on average 6h 47m. The schedules shown below are for the next available departures.

Departing Friday, November 6, 2026

  •  → 

    AmtrakAmtrak Acela6h 2m • 1 change

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    AmtrakAmtrak Acela6h • 1 change

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    Arrives next day

    AmtrakAmtrak13h 18m • 1 change

Departing Saturday, November 7, 2026

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    AmtrakAmtrak Acela5h 46m • 1 change

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    AmtrakAmtrak Acela5h 52m • 1 change

  •  → 

    AmtrakAmtrak6h 5m • 1 change

  •  → 

    AmtrakAmtrak6h 11m • 1 change
  • Show more

Departing Sunday, November 8, 2026

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    AmtrakAmtrak Acela5h 46m • 1 change

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    AmtrakAmtrak Acela5h 52m • 1 change

  •  → 

    AmtrakAmtrak6h 5m • 1 change

  •  → 

    AmtrakAmtrak6h 3m • 1 change
  • Show more

Departing Monday, November 9, 2026

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    AmtrakAmtrak Acela5h 59m • 1 change

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    AmtrakAmtrak6h 5m • 1 change

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    AmtrakAmtrak6h 41m • 1 change

  •  → 

    AmtrakAmtrak Acela5h 47m • 1 change
  • Show more

Departing Tuesday, November 10, 2026

  •  → 

    AmtrakAmtrak Acela5h 59m • 1 change

  •  → 

    AmtrakAmtrak6h 5m • 1 change

  •  → 

    AmtrakAmtrak6h 41m • 1 change

  •  → 

    AmtrakAmtrak Acela5h 47m • 1 change
  • Show more

Departing Wednesday, November 11, 2026

  •  → 

    AmtrakAmtrak Acela5h 59m • 1 change

  •  → 

    AmtrakAmtrak6h 5m • 1 change

  •  → 

    AmtrakAmtrak6h 41m • 1 change

  •  → 

    AmtrakAmtrak Acela5h 47m • 1 change
  • Show more

Departing Thursday, November 12, 2026

  •  → 

    AmtrakAmtrak Acela5h 59m • 1 change

  •  → 

    AmtrakAmtrak6h 5m • 1 change

  •  → 

    AmtrakAmtrak6h 41m • 1 change

  •  → 

    AmtrakAmtrak Acela5h 47m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Poughkeepsie to Cambridge? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Poughkeepsie to Cambridge.ExpandLaunch map view
  • Distance: 302.6 mi
  • Duration: 6h 47m

What companies run services between Poughkeepsie, NY, USA and Cambridge, MA, USA?

You can take a train from Poughkeepsie Amtrak Station to Boston via Ny Moynihan Train Hall At Penn Station in around 5h 47m.

Operators