The average train between Prague 2 and Berlin takes 4h 17m and the fastest train takes 4h 5m. The train service runs several times per day from Prague 2 to Berlin. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague 2 and Berlin. The earliest departure is at 6:20 AM in the morning, and the last departure from Prague 2 is at 5:26 PM which arrives into Berlin at 10:53 PM. All services require a transfer at Nádraží Holešovice and take an average of 4h 17m. The schedules shown below are for the next available departures.


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Want to know about travelling from Prague 2 to Berlin? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague 2 to Berlin. However, there are services departing from Prague 2 station and arriving at Berlin station via Berlin Suedkreuz. The journey, including transfers, takes approximately 4h 17m.
Prague 2 to Berlin train services, operated by Pražská integrovaná doprava, depart from Praha-Holesovice station.
Prague 2 to Berlin train services, operated by Pražská integrovaná doprava, arrive at Berlin Suedkreuz station.
Book your Prague 2 to Berlin train tickets online with Pražská integrovaná doprava, Danish Railways (DSB) and 5 other operators.
The distance between Prague 2 and Berlin is 281.7 km. The road distance is 371 km.
České dráhy (ČD) operates a train from Praha-Holesovice to Berlin Suedkreuz 5 times a day. Tickets cost €40–65 and the journey takes 3h 39m. Two other operators also service this route.