The train between Prague 2 and Berlin takes 4h 8m. The train service runs several times per day from Prague 2 to Berlin. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Prague 2 and Berlin. The earliest departure is at 6:31 AM in the morning, and the last departure from Prague 2 is at 4:31 PM which arrives into Berlin at 8:39 PM. All services require a transfer at Berlin Suedkreuz and take an average of 4h 8m. The schedules shown below are for the next available departures.

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4h 8m • 1 changeWant to know about travelling from Prague 2 to Berlin? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague 2 to Berlin. However, there are services departing from Prague 2 station and arriving at Berlin station via Berlin Suedkreuz. The journey, including transfers, takes approximately 4h 8m.
Prague 2 to Berlin train services, operated by České dráhy (ČD), depart from Praha Hlavni Nadrazi station.
Prague 2 to Berlin train services, operated by České dráhy (ČD), arrive at Berlin Suedkreuz station.
Book your Prague 2 to Berlin train tickets online with České dráhy (ČD) and Deutsche Bahn Regio (DB Regional).
The distance between Prague 2 and Berlin is 281.7 km. The road distance is 370 km.
České dráhy (ČD) operates a train from Praha Hlavni Nadrazi to Berlin Suedkreuz every 4 hours. Tickets cost €29 and the journey takes 3h 49m.