The average train between Prague Castle and Brno takes 3h 4m and the fastest train takes 2h 45m. There is a train service every few hours from Prague Castle to Brno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Prague Castle and Brno. The earliest departure is at 12:01 AM at night, and the last departure from Prague Castle is at 10:51 PM which arrives into Brno at 2:49 AM. All services require a transfer at Hradčanská and take an average of 3h 4m. The schedules shown below are for the next available departures.

2h 48m • 1 change
2h 51m • 1 change
2h 48m • 1 change
2h 49m • 1 change
7h 11m • 1 change
2h 51m • 1 change
2h 48m • 1 change
2h 46m • 1 change
7h 11m • 1 change
2h 51m • 1 change
2h 48m • 1 change
2h 46m • 1 change
7h 11m • 1 change
2h 51m • 1 change
2h 48m • 1 change
2h 51m • 1 changeWant to know about travelling from Prague Castle to Brno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague Castle to Brno. However, there are services departing from Praha Hlavni Nadrazi station and arriving at Brno Hlavni Nadrazi station via Brno Hlavni Nadrazi station. The journey, including transfers, takes approximately 3h 4m.
Prague Castle to Brno train services, operated by RegioJet, depart from Praha Hlavni Nadrazi station.
Prague Castle to Brno train services, operated by RegioJet, arrive at Brno Hlavni Nadrazi station.
The distance between Prague Castle and Brno is 188.3 km. The road distance is 210 km.
RegioJet operates a train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazi hourly. Tickets cost Kč 300–490 and the journey takes 2h 39m. Two other operators also service this route.