The average train between Prague Castle and Brno takes 3h 9m and the fastest train takes 2h 49m. There is a train service every few hours from Prague Castle to Brno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Prague Castle and Brno. The earliest departure is at 5:51 AM in the morning, and the last departure from Prague Castle is at 9:51 PM which arrives into Brno at 3:30 AM. All services require a transfer at Praha-Podbaba and take an average of 3h 9m. The schedules shown below are for the next available departures.


3h 22m • 2 changes


2h 49m • 2 changes


2h 49m • 2 changes


2h 49m • 2 changes


2h 49m • 2 changes


2h 49m • 2 changes


3h 22m • 2 changes


2h 49m • 2 changes


2h 49m • 2 changes


2h 49m • 2 changes


3h 22m • 2 changes


2h 49m • 2 changes


2h 49m • 2 changes


2h 49m • 2 changes


3h 22m • 2 changes


2h 49m • 2 changes
Want to know about travelling from Prague Castle to Brno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague Castle to Brno. However, there are services departing from Prague Castle station and arriving at Brno station via Pardubice Hlavni Nadrazi. The journey, including transfers, takes approximately 3h 9m.
Prague Castle to Brno train services, operated by RegioJet, depart from Praha-Liben station.
Prague Castle to Brno train services, operated by RegioJet, arrive at Brno Hlavni Nadrazi station.
The distance between Prague Castle and Brno is 188.3 km. The road distance is 256 km.
You can take a vehicle from Prague Castle to Brno Hlavni Nadrazi via Praha-Podbaba, Praha-Liben, and Pardubice Hlavni Nadrazi in around 3h 11m.