The average train between Prague Castle and Karlovy Vary takes 3h 53m and the fastest train takes 3h 37m. The train service runs several times per day from Prague Castle to Karlovy Vary. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague Castle and Karlovy Vary. The earliest departure is at 5:21 AM in the morning, and the last departure from Prague Castle is at 11:38 PM which arrives into Karlovy Vary at 9:01 AM. All services require a transfer at Praha-Podbaba and take an average of 3h 53m. The schedules shown below are for the next available departures.

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Want to know about travelling from Prague Castle to Karlovy Vary? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague Castle to Karlovy Vary. However, there are services departing from Prague Castle station and arriving at Karlovy Vary station via Karlovy Vary. The journey, including transfers, takes approximately 3h 53m.
Prague Castle to Karlovy Vary train services, operated by České dráhy (ČD), depart from Praha-Holesovice station.
Prague Castle to Karlovy Vary train services, operated by České dráhy (ČD), arrive at Karlovy Vary station.
Book your Prague Castle to Karlovy Vary train tickets online with České dráhy (ČD) and RegioJet.
The distance between Prague Castle and Karlovy Vary is 109.9 km. The road distance is 233 km.
České dráhy (ČD) operates a train from Praha-Holesovice to Karlovy Vary hourly. Tickets cost Kč 650–1,000 and the journey takes 3h 20m.