The average train between Prague and Berlin ZOB takes 4h 4m and the fastest train takes 3h 56m. The train service runs several times per day from Prague to Berlin ZOB. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague and Berlin ZOB. The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 5:38 PM which arrives into Berlin ZOB at 10:50 PM. All services require a transfer at Berlin Suedkreuz and take an average of 4h 4m. The schedules shown below are for the next available departures.

3h 56m • 1 change
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3h 56m • 1 change
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3h 56m • 1 changeWant to know about travelling from Prague to Berlin ZOB? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Berlin ZOB. However, there are services departing from Prague station and arriving at Berlin ZOB station via Berlin Suedkreuz. The journey, including transfers, takes approximately 4h 4m.
Prague to Berlin ZOB train services, operated by České dráhy (ČD), depart from Praha-Holesovice station.
Prague to Berlin ZOB train services, operated by České dráhy (ČD), arrive at Berlin Suedkreuz station.
Book your Prague to Berlin ZOB train tickets online with České dráhy (ČD), S-Bahn Berlin and 2 other operators.
The distance between Prague and Berlin ZOB is 280.4 km. The road distance is 369 km.
České dráhy (ČD) operates a train from Praha-Holesovice to Berlin Suedkreuz 4 times a day. Tickets cost €40–65 and the journey takes 3h 39m. Two other operators also service this route.