The average train between Prague and Brussels takes 13h 39m and the fastest train takes 11h 51m. The train service runs several times per day from Prague to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague and Brussels. The earliest departure is at 5:35 AM in the morning, and the last departure from Prague is at 5:35 PM which arrives into Brussels at 11:26 AM. All services require a transfer at Schwandorf and take an average of 13h 39m. The schedules shown below are for the next available departures.



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Want to know about travelling from Prague to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Brussels. However, there are services departing from Prague station and arriving at Brussels station via Schwandorf. The journey, including transfers, takes approximately 13h 39m.
Prague to Brussels train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
Prague to Brussels train services, operated by ÖBB EuroCity, arrive at Brussels-Nord station.
Book your Prague to Brussels train tickets online with ÖBB EuroCity, Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Prague and Brussels is 717.3 km. The road distance is 960 km.
You can take a train from Praha Hlavni Nadrazi to Brussels-Nord via Schwandorf, Nürnberg Hbf, and Frankfurt in around 12h 15m.