The average train between Prague and Düsseldorf takes 10h 36m and the fastest train takes 8h 27m. The train service runs several times per day from Prague to Düsseldorf. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague and Düsseldorf. The earliest departure is at 12:42 AM at night, and the last departure from Prague is at 5:38 PM which arrives into Düsseldorf at 10:08 AM. All services require a transfer at Berlin Hbf and take an average of 10h 36m. The schedules shown below are for the next available departures.


11h • 2 changes


9h 1m • 2 changes


10h 23m • 2 changes


8h 58m • 2 changes


11h • 2 changes


9h 1m • 2 changes


10h 23m • 2 changes


8h 58m • 2 changes


10h 29m • 2 changes


8h 30m • 2 changes


9h 26m • 2 changes


8h 27m • 2 changes


11h 26m • 2 changes


9h 26m • 2 changes


9h 26m • 2 changes


8h 27m • 2 changes


11h 26m • 2 changes


9h 26m • 2 changes


9h 26m • 2 changes


8h 27m • 2 changes
Want to know about travelling from Prague to Düsseldorf? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Düsseldorf. However, there are services departing from Prague station and arriving at Düsseldorf station via Berlin Hbf. The journey, including transfers, takes approximately 10h 36m.
Prague to Düsseldorf train services, operated by Danish Railways (DSB), depart from Praha-Holesovice station.
Prague to Düsseldorf train services, operated by Danish Railways (DSB), arrive at Düsseldorf Hbf station.
Book your Prague to Düsseldorf train tickets online with Danish Railways (DSB), Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Prague and Düsseldorf is 553.2 km. The road distance is 903 km.
You can take a train from Praha-Holesovice to Düsseldorf Hbf via Berlin Hbf and Wolfsburg, Hauptbahnhof in around 9h.