The average train between Prague and Duisburg takes 9h 45m and the fastest train takes 8h 20m. The train service runs several times per day from Prague to Duisburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Prague and Duisburg. The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 4:41 PM which arrives into Duisburg at 5:37 AM. All services require a transfer, and take on average 9h 45m. The schedules shown below are for the next available departures.

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9h 8m • 1 changeWant to know about travelling from Prague to Duisburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Duisburg. However, there are services departing from Prague station and arriving at Duisburg station via Berlin-Spandau. The journey, including transfers, takes approximately 9h 45m.
Prague to Duisburg train services, operated by Railjet, depart from Praha-Holesovice station.
Prague to Duisburg train services, operated by Railjet, arrive at Duisburg Hbf station.
Book your Prague to Duisburg train tickets online with Railjet, Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Prague and Duisburg is 558.6 km. The road distance is 880 km.
You can take a train from Praha-Holesovice to Duisburg Hbf via S Spandau Bhf in around 8h 30m.