The average train between Prague and Eisenach takes 7h 31m and the fastest train takes 6h 5m. The train service runs several times per day from Prague to Eisenach. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Prague and Eisenach. The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 6:41 PM which arrives into Eisenach at 8:46 AM. All services require a transfer, and take on average 7h 31m. The schedules shown below are for the next available departures.

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6h 5m • 1 changeWant to know about travelling from Prague to Eisenach? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Eisenach. However, there are services departing from Prague station and arriving at Eisenach station via Dresden-Neustadt. The journey, including transfers, takes approximately 7h 31m.
Prague to Eisenach train services, operated by Danish Railways (DSB), depart from Praha-Holesovice station.
Prague to Eisenach train services, operated by Danish Railways (DSB), arrive at Eisenach Hbf station.
Book your Prague to Eisenach train tickets online with Danish Railways (DSB), Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Prague and Eisenach is 306.6 km. The road distance is 476 km.
You can take a train from Praha-Holesovice to Eisenach Hbf via Dresden Bahnhof Neustadt in around 5h 46m.