The average train between Prague and Enschede takes 11h 31m and the fastest train takes 9h 45m. The train service runs several times per day from Prague to Enschede. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Prague and Enschede. The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 5:38 PM which arrives into Enschede at 10:26 AM. All services require a transfer at Berlin Hbf and take an average of 11h 31m. The schedules shown below are for the next available departures.


9h 45m • 2 changes

9h 45m • 2 changes

9h 45m • 2 changesArrives next day


16h 48m • 2 changes

9h 45m • 2 changes

9h 45m • 2 changes

9h 45m • 2 changesArrives next day


17h 45m • 2 changes

9h 45m • 2 changes

9h 45m • 2 changes

9h 45m • 2 changesArrives next day


16h 49m • 2 changes

9h 46m • 2 changes

9h 46m • 2 changes

9h 46m • 2 changesArrives next day


16h 49m • 2 changesWant to know about travelling from Prague to Enschede? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Enschede. However, there are services departing from Prague station and arriving at Enschede station via Berlin Hbf. The journey, including transfers, takes approximately 11h 31m.
Prague to Enschede train services, operated by České dráhy (ČD), depart from Praha-Holesovice station.
Prague to Enschede train services, operated by České dráhy (ČD), arrive at Hengelo station.
Book your Prague to Enschede train tickets online with České dráhy (ČD), Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Prague and Enschede is 575.4 km. The road distance is 855 km.
You can take a train from Praha-Holesovice to Enschede via Berlin Hbf and Hengelo in around 8h 55m.