The average train between Prague and Enschede takes 11h 31m and the fastest train takes 9h 45m. The train service runs several times per day from Prague to Enschede. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Prague and Enschede. The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 5:38 PM which arrives into Enschede at 10:26 AM. All services require a transfer at Berlin Suedkreuz and take an average of 11h 31m. The schedules shown below are for the next available departures.


9h 45m • 2 changes


9h 45m • 2 changes


9h 45m • 2 changes
Arrives next day


17h 45m • 2 changes


9h 45m • 2 changes


9h 45m • 2 changes


9h 45m • 2 changes
Arrives next day


16h 49m • 2 changes


9h 46m • 2 changes


9h 46m • 2 changes


9h 46m • 2 changes
Arrives next day


16h 49m • 2 changes
Want to know about travelling from Prague to Enschede? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Enschede. However, there are services departing from Prague station and arriving at Enschede station via Berlin Suedkreuz. The journey, including transfers, takes approximately 11h 31m.
Prague to Enschede train services, operated by Danish Railways (DSB), depart from Praha-Holesovice station.
Prague to Enschede train services, operated by Danish Railways (DSB), arrive at Hengelo station.
Book your Prague to Enschede train tickets online with Danish Railways (DSB), Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Prague and Enschede is 575.4 km. The road distance is 855 km.
You can take a train from Praha-Holesovice to Enschede via Berlin Suedkreuz, S Südkreuz Bhf, and Hengelo in around 8h 57m.