The average train between Prague and Karlsruhe takes 10h 45m and the fastest train takes 9h 8m. The train service runs several times per day from Prague to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague and Karlsruhe. The earliest departure is at 5:35 AM in the morning, and the last departure from Prague is at 5:35 PM which arrives into Karlsruhe at 12:53 PM. All services require a transfer at Schwandorf and take an average of 10h 45m. The schedules shown below are for the next available departures.


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9h 19m • 2 changesWant to know about travelling from Prague to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Karlsruhe. However, there are services departing from Prague station and arriving at Karlsruhe station via Schwandorf. The journey, including transfers, takes approximately 10h 45m.
Prague to Karlsruhe train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
Prague to Karlsruhe train services, operated by ÖBB EuroCity, arrive at Karlsruhe Hauptbahnhof station.
Book your Prague to Karlsruhe train tickets online with ÖBB EuroCity, Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Prague and Karlsruhe is 450.2 km. The road distance is 623 km.
You can take a train from Praha Hlavni Nadrazi to Karlsruhe Hauptbahnhof via Schwandorf, Nürnberg Hbf, and Nürnberg Hbf in around 9h 32m.