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Prague to Madrid trains

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Trip Overview

The average train between Prague and Madrid takes 46h 26m and the fastest train takes 46h 23m. The train runs, on average, 2 times per week from Prague to Madrid. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

46h 26m
Duration
2,609 km
Distance
€517
Average price
Twice a week
Frequency

Prague to Madrid train times

Trains run twice a week between Prague and Madrid. The service departs Prague at 5:35 PM in the evening, which arrives into Madrid at 16:05:00. All services require a transfer at Muenchen Hbf and take an average of 46h 26m. The schedules shown below are for the next available departures.

Departing Wednesday, October 28, 2026

  •  → 

    Arrives +2 days

    ÖBB EuroCityDeutsche Bahn Intercity (DB IC)TGV inOuiRenfe ViajerosRenfe Cercanias46h 30m • 4 changes

Departing Thursday, October 29, 2026

  •  → 

    Arrives +2 days

    ÖBB EuroCityDeutsche Bahn Intercity (DB IC)TGV inOuiRenfe ViajerosRenfe Cercanias46h 23m • 4 changes

Frequently asked questions

Want to know about travelling from Prague to Madrid? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Prague to Madrid.ExpandLaunch map view
  • Distance: 2,609.2 km
  • Duration: 46h 26m

What companies run services between Prague, Czechia and Madrid, Spain?

You can take a train from Praha Hlavni Nadrazi to Sol via Muenchen Hbf, München Hbf, Strasbourg Bahnhof, Strasbourg, Avignon Tgv, Madrid-Puerta De Atocha-Almudena Grandes, and Madrid-Atocha Cercanías in around 25h 47m.

Operators