Prague to Mainz-Kastel trains

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Trip Overview

The average train between Prague and Mainz-Kastel takes 9h 46m and the fastest train takes 8h 33m. The train service runs several times per day from Prague to Mainz-Kastel. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

9h 46m
Duration: 710 km
Distance: €152
Average price: Every 4 hours
Frequency

Train via Leipzig

best

Take the train from Praha-Holesovice to Dresden Hbftrain Rj
Take the train from Dresden Hauptbahnhof to Leipzig Hbftrain 55 / ...
Take the train from Leipzig Hbf to Erfurt Hbftrain 28 / ...
Take the train from Erfurt Hbf to Frankfurttrain 12 / ...

7h 56m

€101–315

Prague to Mainz-Kastel train times

Trains run every 4 hours between Prague and Mainz-Kastel. The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 8:57 PM which arrives into Mainz-Kastel at 9:14 AM. All services require a transfer at Dresden Hauptbahnhof and take an average of 9h 46m. The schedules shown below are for the next available departures.

Departing Wednesday, October 28, 2026

8:41 AM → 5:14 PM
8h 33m • 4 changes
10:41 AM → 7:14 PM
8h 33m • 4 changes
12:41 PM → 9:39 PM
8h 58m • 4 changes
2:41 PM → 11:39 PM
8h 58m • 4 changes
Show more

Departing Thursday, October 29, 2026

6:41 AM → 3:14 PM
8h 33m • 4 changes
8:41 AM → 5:14 PM
8h 33m • 4 changes
10:41 AM → 7:14 PM
8h 33m • 4 changes
12:41 PM → 9:39 PM
8h 58m • 4 changes
Show more

Departing Friday, October 30, 2026

6:41 AM → 3:39 PM
8h 58m • 4 changes
8:41 AM → 5:39 PM
8h 58m • 4 changes
10:41 AM → 7:39 PM
8h 58m • 4 changes
12:41 PM → 9:39 PM
8h 58m • 4 changes
Show more

Departing Saturday, October 31, 2026

6:41 AM → 3:39 PM
8h 58m • 4 changes
8:41 AM → 5:39 PM
8h 58m • 4 changes
10:41 AM → 7:39 PM
8h 58m • 4 changes
12:41 PM → 9:39 PM
8h 58m • 4 changes
Show more

Departing Sunday, November 1, 2026

6:41 AM → 3:39 PM
8h 58m • 4 changes
8:41 AM → 5:39 PM
8h 58m • 4 changes
10:41 AM → 7:39 PM
8h 58m • 4 changes
12:41 PM → 9:39 PM
8h 58m • 4 changes
Show more

Departing Monday, November 2, 2026

6:41 AM → 3:39 PM
8h 58m • 4 changes
6:41 PM → 4:24 AM
Arrives next day
9h 43m • 4 changes
8:57 PM → 11:39 AM
Arrives next day
14h 42m • 4 changes

Departing Tuesday, November 3, 2026

6:41 AM → 3:39 PM
8h 58m • 4 changes
10:41 AM → 7:39 PM
8h 58m • 4 changes

Frequently asked questions

Want to know about travelling from Prague to Mainz-Kastel? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Prague to Mainz-Kastel.

Launch map view

Distance: 709.7 km
Duration: 9h 46m

What companies run services between Prague, Czechia and Mainz-Kastel, Hesse, Germany?

You can take a train from Praha-Holesovice to Wiesbaden-Mainz-Kastel Bahnhof via Dresden Hauptbahnhof, Leipzig Hbf, Erfurt Hbf, and Frankfurt in around 7h 56m.

Operators