The average train between Prague and Mannheim takes 9h 43m and the fastest train takes 7h 49m. The train service runs several times per day from Prague to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Prague and Mannheim. The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 8:57 PM which arrives into Mannheim at 11:29 AM. All services require a transfer at Dresden Hauptbahnhof and take an average of 9h 43m. The schedules shown below are for the next available departures.



8h 48m • 3 changes


8h 48m • 3 changes


8h 48m • 3 changes


8h 48m • 3 changes


7h 49m • 3 changes


7h 49m • 3 changes


8h 48m • 3 changes


8h 48m • 3 changesWant to know about travelling from Prague to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Mannheim. However, there are services departing from Praha-Holesovice station and arriving at Mannheim, Hauptbahnhof station via Dresden Hbf station, Leipzig Hbf station and Erfurt Hbf station. The journey, including transfers, takes approximately 9h 43m.
Prague to Mannheim train services, operated by České dráhy (ČD), depart from Praha-Holesovice station.
Prague to Mannheim train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
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The distance between Prague and Mannheim is 432.5 km. The road distance is 512 km.
You can take a train from Praha-Holesovice to Mannheim, Hauptbahnhof via Dresden Hauptbahnhof, Leipzig Hbf, and Erfurt Hbf in around 8h 19m.