The average train between Prague and Mannheim takes 10h 11m and the fastest train takes 8h 41m. The train service runs several times per day from Prague to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Prague and Mannheim. The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 8:57 PM which arrives into Mannheim at 10:30 AM. All services require a transfer at Dresden Hauptbahnhof and take an average of 10h 11m. The schedules shown below are for the next available departures.



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9h 14m • 3 changesWant to know about travelling from Prague to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Mannheim. However, there are services departing from Prague station and arriving at Mannheim station via Dresden Hbf. The journey, including transfers, takes approximately 10h 11m.
Prague to Mannheim train services, operated by České dráhy (ČD), depart from Praha-Holesovice station.
Prague to Mannheim train services, operated by České dráhy (ČD), arrive at Mannheim, Hauptbahnhof station.
Book your Prague to Mannheim train tickets online with České dráhy (ČD), Deutsche Bahn Regio (DB Regional) and 4 other operators.
The distance between Prague and Mannheim is 432.5 km. The road distance is 753 km.
You can take a train from Praha-Holesovice to Mannheim, Hauptbahnhof via Dresden Hauptbahnhof, Leipzig Hbf, and Erfurt Hbf in around 8h 18m.