The average train between Prague and Meziměstí takes 4h 29m and the fastest train takes 3h 48m. The train service runs several times per day from Prague to Meziměstí. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague and Meziměstí. The earliest departure is at 6:14 AM in the morning, and the last departure from Prague is at 6:14 PM which arrives into Meziměstí at 11:39 PM. All services require a transfer, and take on average 4h 29m. The schedules shown below are for the next available departures.

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3h 48m • 1 change

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Want to know about travelling from Prague to Meziměstí? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Meziměstí. However, there are services departing from Prague station and arriving at Meziměstí station via Starkoc. The journey, including transfers, takes approximately 4h 29m.
Prague to Meziměstí train services, operated by České dráhy (ČD), depart from Praha Hlavni Nadrazi station.
Prague to Meziměstí train services, operated by České dráhy (ČD), arrive at Mezimesti station.
Book your Prague to Meziměstí train tickets online with České dráhy (ČD).
The distance between Prague and Meziměstí is 142.2 km. The road distance is 188 km.
You can take a train from Praha Hlavni Nadrazi to Mezimesti via Starkoc in around 3h 38m.