The average train between Prague and Mosel takes 5h 6m and the fastest train takes 4h 27m. The train service runs several times per day from Prague to Mosel. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Prague and Mosel. The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 8:57 PM which arrives into Mosel at 8:08 AM. All services require a transfer, and take on average 5h 6m. The schedules shown below are for the next available departures.

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4h 27m • 1 changeWant to know about travelling from Prague to Mosel? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Mosel. However, there are services departing from Prague station and arriving at Mosel station via Dresden Hbf. The journey, including transfers, takes approximately 5h 6m.
Prague to Mosel train services, operated by České dráhy (ČD), depart from Praha-Holesovice station.
Prague to Mosel train services, operated by České dráhy (ČD), arrive at Mosel station.
Book your Prague to Mosel train tickets online with České dráhy (ČD), Transdev GmbH and 2 other operators.
The distance between Prague and Mosel is 157.7 km. The road distance is 303 km.
You can take a train from Praha-Holesovice to Mosel via Dresden Hbf in around 4h 47m.