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Prague to Nové Mesto trains

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Trip Overview

The average train between Prague and Nové Mesto takes 4h 45m and the fastest train takes 4h 38m. The train service runs several times per day from Prague to Nové Mesto. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 45m
Duration
397 km
Distance
€22
Average price
Every 3 hours
Frequency

Prague to Nové Mesto train times

Trains run every 3 hours between Prague and Nové Mesto. The earliest departure is at 5:37 AM in the morning, and the last departure from Prague is at 5:37 PM which arrives into Nové Mesto at 10:15 PM. All services require a transfer at Bratislava hl.st. and take an average of 4h 45m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 38m • 1 change

Departing Wednesday, November 11, 2026

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    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 39m • 1 change
  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 39m • 1 change
  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 42m • 1 change
  •  → 

    RegioJetSlovakia Public Transport4h 42m • 1 change
  • Show more

Departing Thursday, November 12, 2026

  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 39m • 1 change
  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 39m • 1 change
  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 42m • 1 change
  •  → 

    RegioJetSlovakia Public Transport4h 42m • 1 change
  • Show more

Departing Friday, November 13, 2026

  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 39m • 1 change
  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 39m • 1 change
  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 42m • 1 change
  •  → 

    RegioJetSlovakia Public Transport4h 42m • 1 change
  • Show more

Departing Saturday, November 14, 2026

  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 39m • 1 change
  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 38m • 1 change
  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 38m • 1 change
  •  → 

    RegioJetSlovakia Public Transport4h 44m • 1 change
  • Show more

Departing Sunday, November 15, 2026

  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 39m • 1 change
  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 38m • 1 change
  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 38m • 1 change
  •  → 

    RegioJetSlovakia Public Transport4h 44m • 1 change
  • Show more

Departing Monday, November 16, 2026

  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 39m • 1 change
  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 39m • 1 change
  •  → 

    Railways of Slovak Republic (ZSSK)Slovakia Public Transport4h 42m • 1 change
  •  → 

    RegioJetSlovakia Public Transport4h 42m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Prague to Nové Mesto? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Prague to Nové Mesto.ExpandLaunch map view
  • Distance: 396.9 km
  • Duration: 4h 45m

What companies run services between Prague, Czechia and Nové Mesto, Slovakia?

Railways of Slovak Republic (ZSSK) operates a train from Praha hl.n. to Bratislava hl.st. every 4 hours. Tickets cost €19–35 and the journey takes 4h 25m. Two other operators also service this route.

Operators