The average train between Prague and Plzeň Region takes 2h 17m and the fastest train takes 1h 56m. There is a train service every few hours from Prague to Plzeň Region. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Prague and Plzeň Region. The earliest departure is at 5:05 AM in the morning, and the last departure from Prague is at 11:46 PM which arrives into Plzeň Region at 5:20 AM. All services require a transfer, and take on average 2h 17m. The schedules shown below are for the next available departures.

2h 1m • 1 change

2h 1m • 1 change

1h 56m • 1 change
Arrives next day

5h 34m • 1 change

2h 3m • 1 change

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2h 1m • 1 change

2h 1m • 1 change

2h 3m • 1 change

2h 1m • 1 change

2h 1m • 1 change

2h 1m • 1 change

2h 3m • 1 change

2h 1m • 1 change

2h 1m • 1 change

2h 1m • 1 change
Want to know about travelling from Prague to Plzeň Region? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Plzeň Region. However, there are services departing from Prague station and arriving at Plzeň Region station via Plzen Hlavni Nadrazi. The journey, including transfers, takes approximately 2h 17m.
Prague to Plzeň Region train services, operated by České dráhy (ČD), depart from Praha Hlavni Nadrazi station.
Prague to Plzeň Region train services, operated by České dráhy (ČD), arrive at Plzen Hlavni Nadrazi station.
Book your Prague to Plzeň Region train tickets online with České dráhy (ČD) and ÖBB EuroCity.
The distance between Prague and Plzeň Region is 97.5 km. The road distance is 114 km.
České dráhy (ČD) operates a train from Praha Hlavni Nadrazi to Plzen Hlavni Nadrazi every 30 minutes. Tickets cost Kč 290–430 and the journey takes 1h 23m. ÖBB EuroCity also services this route hourly.