The average train between Prague and Senica (Station) takes 6h 43m and the fastest train takes 5h 52m. The train service runs several times per day from Prague to Senica (Station). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague and Senica (Station). The earliest departure is at 5:37 AM in the morning, and the last departure from Prague is at 6:31 PM which arrives into Senica (Station) at 5:28 AM. All services require a transfer, and take on average 6h 43m. The schedules shown below are for the next available departures.

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Want to know about travelling from Prague to Senica (Station)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Senica (Station). However, there are services departing from Prague station and arriving at Senica (Station) station via Kuty. The journey, including transfers, takes approximately 6h 43m.
Prague to Senica (Station) train services, operated by Railways of Slovak Republic (ZSSK), depart from Praha Hlavni Nadrazi station.
Prague to Senica (Station) train services, operated by Railways of Slovak Republic (ZSSK), arrive at Kuty station.
The distance between Prague and Senica (Station) is 263.5 km. The road distance is 354 km.
ÖBB EuroCity operates a train from Praha Hlavni Nadrazi to Kuty every 4 hours. Tickets cost €70–130 and the journey takes 3h 28m. Two other operators also service this route.