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Prague to Sicily trains

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Trip Overview

The train between Prague and Sicily takes 2d 10h. The train runs, on average, 5 times per week from Prague to Sicily. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 10h
Duration
2,455 km
Distance
€349
Average price
5 times a week
Frequency

Prague to Sicily train times

Trains run 5 times a week between Prague and Sicily. The service departs Prague at 8:37 AM in the morning, which arrives into Sicily at 19:29:00. All services require a transfer at Wien Hbf and take an average of 2d 10h. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

  •  → 

    Arrives +2 days

    České dráhy (ČD)RailjetItaloTrenoTrenitalia IntercityTrenitalia2d 10h • 4 changes

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    České dráhy (ČD)RailjetItaloTrenoTrenitalia IntercityTrenitalia2d 10h • 4 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    České dráhy (ČD)RailjetItaloTrenoTrenitalia IntercityTrenitalia2d 10h • 4 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    České dráhy (ČD)RailjetItaloTrenoTrenitalia IntercityTrenitalia2d 10h • 4 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    České dráhy (ČD)RailjetItaloTrenoTrenitalia IntercityTrenitalia2d 11h • 4 changes

Frequently asked questions

Want to know about travelling from Prague to Sicily? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Prague to Sicily.ExpandLaunch map view
  • Distance: 2,454.6 km
  • Duration: 2d 10h

What companies run services between Prague, Czechia and Sicily, Italy?

You can take a train from Praha Hlavni Nadrazi to Palermo Notarbartolo via Wien Hbf, Udine, Roma Termini, and Palermo Centrale in around 30h 25m.

Operators