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Prague to Vatican Museums trains

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Trip Overview

The average train between Prague and Vatican Museums takes 20h 36m and the fastest train takes 16h 57m. There is at least one train per day from Prague to Vatican Museums. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

20h 36m
Duration
1,589 km
Distance
€240
Average price
Once daily
Frequency

Prague to Vatican Museums train times

Trains run once daily between Prague and Vatican Museums. The earliest departure is at 4:35 AM at night, and the last departure from Prague is at 8:37 AM which arrives into Vatican Museums at 9:47 AM. All services require a transfer at Wien Hbf and take an average of 20h 36m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

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    Arrives next day

    České dráhy (ČD)RailjetTrenitalia FrecceTrenitalia25h 10m • 3 changes

Departing Tuesday, November 10, 2026

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    České dráhy (ČD)RailjetItaloTrenoTrenitalia16h 57m • 3 changes
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    Arrives next day

    České dráhy (ČD)RailjetTrenitalia FrecceTrenitalia25h 10m • 3 changes

Departing Wednesday, November 11, 2026

  •  → 

    České dráhy (ČD)RailjetItaloTrenoTrenitalia16h 57m • 3 changes
  •  → 

    Arrives next day

    České dráhy (ČD)RailjetTrenitalia FrecceTrenitalia25h 10m • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    České dráhy (ČD)RailjetItaloTrenoTrenitalia16h 57m • 3 changes
  •  → 

    Arrives next day

    České dráhy (ČD)RailjetTrenitalia FrecceTrenitalia25h 10m • 3 changes

Departing Friday, November 13, 2026

  •  → 

    České dráhy (ČD)RailjetItaloTrenoTrenitalia16h 57m • 3 changes

Frequently asked questions

Want to know about travelling from Prague to Vatican Museums? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Prague to Vatican Museums.ExpandLaunch map view
  • Distance: 1,588.9 km
  • Duration: 20h 36m

What companies run services between Prague, Czechia and Vatican Museums, Vatican City?

You can take a train from Praha Hlavni Nadrazi to Vatican Museums via Wien Hbf, Venezia Mestre, Roma Tiburtina, and Roma S. Pietro in around 16h 52m.

Operators