The average train between Prague and Vyškov takes 3h 54m and the fastest train takes 3h 19m. There is a train service every few hours from Prague to Vyškov. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Prague and Vyškov. The earliest departure is at 12:01 AM at night, and the last departure from Prague is at 11:01 PM which arrives into Vyškov at 5:35 AM. All services require a transfer, and take on average 3h 54m. The schedules shown below are for the next available departures.

3h 21m • 1 change
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4h 2m • 1 change
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3h 38m • 1 change
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4h 2m • 1 changeWant to know about travelling from Prague to Vyškov? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Vyškov. However, there are services departing from Praha Hlavni Nadrazi station and arriving at Brno Hlavni Nadrazi station via Brno Hlavni Nadrazi station. The journey, including transfers, takes approximately 3h 54m.
Prague to Vyškov train services, operated by RegioJet, depart from Praha Hlavni Nadrazi station.
Prague to Vyškov train services, operated by RegioJet, arrive at Brno Hlavni Nadrazi station.
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The distance between Prague and Vyškov is 206.2 km. The road distance is 241 km.
RegioJet operates a train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazi hourly. Tickets cost Kč 300–490 and the journey takes 2h 39m. Two other operators also service this route.