The average train between Preston and Palermo takes 46h 5m and the fastest train takes 37h 57m. The train service runs several times per day from Preston to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Preston and Palermo. The earliest departure is at 8:01 AM in the morning, and the last departure from Preston is at 8:00 PM which arrives into Palermo at 10:58 PM. All services require a transfer at London Euston and take an average of 46h 5m. The schedules shown below are for the next available departures.
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37h 57m • 5 changesArrives +2 days





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37h 57m • 5 changesArrives +2 days





2d 6h • 5 changesArrives next day





37h 57m • 5 changesArrives +2 days





2d 6h • 5 changesWant to know about travelling from Preston to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Preston to Palermo. However, there are services departing from Preston station and arriving at Palermo station via London Euston. The journey, including transfers, takes approximately 46h 5m.
Preston to Palermo train services, operated by Avanti West Coast, depart from Preston station.
Preston to Palermo train services, operated by Avanti West Coast, arrive at Palermo Centrale station.
Book your Preston to Palermo train tickets online with Avanti West Coast, Eurostar and 4 other operators.
The distance between Preston and Palermo is 2,124.5 km. The road distance is 3,136 km.
You can take a train from Preston to Palermo Centrale via London Euston, London St Pancras Intl, Lille Europe, Lyon Part Dieu, Milano Centrale, and Roma Termini in around 30h 22m.