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Preston to Palermo trains

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Trip Overview

The average train between Preston and Palermo takes 44h 49m and the fastest train takes 37h 57m. The train service runs several times per day from Preston to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

44h 49m
Duration
3,136 km
Distance
€609
Average price
Twice daily
Frequency

Preston to Palermo train times

Trains run twice daily between Preston and Palermo. The earliest departure is at 8:01 AM in the morning, and the last departure from Preston is at 4:59 PM which arrives into Palermo at 7:04 PM. All services require a transfer at London Euston and take an average of 44h 49m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

  •  → 

    Arrives +2 days

    Avanti West CoastEurostarTGV inOuiTrenitaliaItaloTrenoTrenitalia Intercity2d 6h • 5 changes

Departing Tuesday, November 3, 2026

  •  → 

    Arrives next day

    Avanti West CoastEurostarTGV inOuiTrenitaliaItaloTrenoTrenitalia Intercity37h 57m • 5 changes
  •  → 

    Arrives +2 days

    Avanti West CoastEurostarTGV inOuiTrenitaliaItaloTrenoTrenitalia Intercity2d 6h • 5 changes

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    Avanti West CoastEurostarTGV inOuiTrenitaliaItaloTrenoTrenitalia Intercity37h 57m • 5 changes
  •  → 

    Arrives +2 days

    Avanti West CoastEurostarTGV inOuiTrenitaliaItaloTrenoTrenitalia Intercity2d 6h • 5 changes

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    Avanti West CoastEurostarTGV inOuiTrenitaliaItaloTrenoTrenitalia Intercity37h 57m • 5 changes
  •  → 

    Arrives +2 days

    Avanti West CoastEurostarTGV inOuiTrenitaliaItaloTrenoTrenitalia Intercity2d 6h • 5 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Avanti West CoastEurostarTGV inOuiTrenitaliaItaloTrenoTrenitalia Intercity37h 57m • 5 changes
  •  → 

    Arrives +2 days

    Avanti West CoastEurostarTGV inOuiTrenitaliaItaloTrenoTrenitalia Intercity2d 1h • 5 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    Avanti West CoastEurostarTGV inOuiTrenitaliaItaloTrenoTrenitalia Intercity37h 57m • 5 changes

Frequently asked questions

Want to know about travelling from Preston to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Preston to Palermo.ExpandLaunch map view
  • Distance: 3,135.5 km
  • Duration: 44h 49m

What companies run services between Preston, England and Palermo, Italy?

You can take a train from Preston to Palermo Centrale via London Euston, London St Pancras Intl, Lille Europe, Lyon Part Dieu, Milano Centrale, and Roma Termini in around 30h 23m.

Operators