Prestwich to Southampton Trains

Prestwich to Southampton trains

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Trip Overview

The average train between Prestwich and Southampton takes 5h 9m and the fastest train takes 4h 51m. There is a train service every few hours from Prestwich to Southampton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 9m
Duration: 231 mi
Distance: £153
Average price: Hourly
Frequency

Train

best

Take the train from Manchester Piccadilly to Southampton Centraltrain Manchester Piccadilly - Bournemouth / ...

5h 35m

£123–173

Prestwich to Southampton train times

Trains run hourly between Prestwich and Southampton. The earliest departure is at 12:50 AM at night, and the last departure from Prestwich is at 11:50 PM which arrives into Southampton at 9:43 AM. All services require a transfer at Piccadilly and take an average of 5h 9m. The schedules shown below are for the next available departures.

Departing Sunday, September 6, 2026

1:50 PM → 6:42 PM
4h 51m • 1 change
2:50 PM → 7:42 PM
4h 51m • 1 change
3:50 PM → 8:45 PM
4h 54m • 1 change
4:50 PM → 9:42 PM
4h 51m • 1 change
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Departing Monday, September 7, 2026

6:50 AM → 11:43 AM
4h 53m • 1 change
7:50 AM → 12:47 PM
4h 57m • 1 change
8:50 AM → 1:43 PM
4h 53m • 1 change
9:50 AM → 2:43 PM
4h 53m • 1 change
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Departing Tuesday, September 8, 2026

6:50 AM → 11:43 AM
4h 53m • 1 change
7:50 AM → 12:47 PM
4h 57m • 1 change
8:50 AM → 1:43 PM
4h 53m • 1 change
9:50 AM → 2:43 PM
4h 53m • 1 change
Show more

Departing Wednesday, September 9, 2026

6:50 AM → 11:43 AM
4h 53m • 1 change
7:50 AM → 12:47 PM
4h 57m • 1 change
8:50 AM → 1:43 PM
4h 53m • 1 change
9:50 AM → 2:43 PM
4h 53m • 1 change
Show more

Departing Thursday, September 10, 2026

12:50 AM → 9:43 AM
8h 53m • 1 change
6:50 AM → 11:43 AM
4h 53m • 1 change
7:50 AM → 12:47 PM
4h 57m • 1 change

Frequently asked questions

Want to know about travelling from Prestwich to Southampton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.