The average train between Rheine and Brussels takes 6h 5m and the fastest train takes 4h 30m. There is at least one train per day from Rheine to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Rheine and Brussels. The earliest departure is at 7:36 AM in the morning, and the last departure from Rheine is at 10:49 PM which arrives into Brussels at 10:06 AM. All services require a transfer at Hengelo and take an average of 6h 5m. The schedules shown below are for the next available departures.


4h 30m • 2 changes


4h 30m • 2 changes


4h 30m • 2 changes
Arrives next day


11h 17m • 2 changes


4h 30m • 2 changes


4h 30m • 2 changes


5h 17m • 2 changes


5h 17m • 2 changes
Want to know about travelling from Rheine to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rheine to Brussels. However, there are services departing from Rheine station and arriving at Brussels station via Hengelo. The journey, including transfers, takes approximately 6h 5m.
Rheine to Brussels train services, operated by Eurobahn, depart from Rheine station.
Rheine to Brussels train services, operated by Eurobahn, arrive at Brussel-Zuid / Bruxelles-Midi station.
Book your Rheine to Brussels train tickets online with Eurobahn, Nederlandse Spoorwegen (NS) and Eurostar.
The distance between Rheine and Brussels is 266.6 km. The road distance is 372 km.
You can take a train from Rheine to Brussel-Zuid / Bruxelles-Midi via Hengelo and Rotterdam Centraal in around 5h 27m.