Rome2Rio

Roanoke to Florence trains

Find Transport to Florence

View schedule

Trip Overview

The train between Roanoke and Florence takes 28h 20m. The train runs, on average, 6 times per week from Roanoke to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

28h 20m
Duration
403 mi
Distance
$259
Average price
6 times a week
Frequency

Roanoke to Florence train times

Trains run 6 times a week between Roanoke and Florence. The service departs Roanoke at 4:23 PM in the afternoon, which arrives into Florence at 20:43:00. All services require a transfer at Lynchburg and take an average of 28h 20m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

  •  → 

    Arrives next day

    AmtrakAmtrakAmtrakAmtrak28h 20m • 3 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives next day

    AmtrakAmtrakAmtrakAmtrak28h 20m • 3 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    AmtrakAmtrakAmtrakAmtrak28h 20m • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    AmtrakAmtrakAmtrakAmtrak28h 20m • 3 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    AmtrakAmtrakAmtrakAmtrak28h 20m • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    AmtrakAmtrakAmtrakAmtrak28h 20m • 3 changes

Frequently asked questions

Want to know about travelling from Roanoke to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Roanoke to Florence.ExpandLaunch map view
  • Distance: 403.3 mi
  • Duration: 28h 20m

What companies run services between Roanoke, VA, USA and Florence, SC, USA?

You can take a train from Roanoke to Florence Station via Lynchburg, Greensboro, and Selma Station in around 11h 25m.

Operators