The average train between Rochester and Harrisburg takes 13h 50m and the fastest train takes 11h. The train service runs several times per day from Rochester to Harrisburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Rochester and Harrisburg. The earliest departure is at 5:31 AM in the morning, and the last departure from Rochester is at 1:25 PM which arrives into Harrisburg at 9:15 AM. All services require a transfer, and take on average 13h 50m. The schedules shown below are for the next available departures.

11h 4m • 1 change

11h • 1 change

13h 50m • 1 change
Arrives next day

19h 50m • 1 change

11h 4m • 1 change

11h • 1 change

13h 50m • 1 change
Arrives next day

19h 50m • 1 change

11h 4m • 1 change

11h • 1 change

13h 50m • 1 change
Arrives next day

20h 57m • 1 change

11h 1m • 1 change

12h 17m • 1 change

13h 17m • 1 change
Arrives next day

20h 57m • 1 change
Want to know about travelling from Rochester to Harrisburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Rochester to Harrisburg. However, there are services departing from Rochester station and arriving at Harrisburg station via Ny Moynihan Train Hall At Penn Station station. The journey, including transfers, takes approximately 13h 50m.
Rochester to Harrisburg train services, operated by Amtrak, depart from Rochester station.
Rochester to Harrisburg train services, operated by Amtrak, arrive at Harrisburg station.
Book your Rochester to Harrisburg train tickets online with Amtrak.
The distance between Rochester and Harrisburg is 326.1 km. The road distance is 904 km.
You can take a train from Rochester to Harrisburg via Ny Moynihan Train Hall At Penn Station in around 11h 28m.