Roma Ostiense to Milano Centrale Station Trains

Roma Ostiense to Milano Centrale Station trains

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Trip Overview

The average train between Roma Ostiense and Milano Centrale Station takes 3h 45m and the fastest train takes 3h 15m. There is a train service every few hours from Roma Ostiense to Milano Centrale Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 45m
Duration: 585 km
Distance: €92
Average price: Hourly
Frequency

Train via Piramide

best

Take the train from Roma Termini to Milano Centraletrain 9950 / ...

3h 30m

€76–152

Roma Ostiense to Milano Centrale Station train times

Trains run hourly between Roma Ostiense and Milano Centrale Station. The earliest departure is at 6:16 AM in the morning, and the last departure from Roma Ostiense is at 11:45 PM which arrives into Milano Centrale Station at 9:20 AM. All services require a transfer at Piramide and take an average of 3h 45m. The schedules shown below are for the next available departures.

Departing Monday, August 24, 2026

7:51 PM → 11:15 PM
3h 23m • 1 change
11:45 PM → 9:20 AM
Arrives next day
9h 34m • 1 change

Departing Tuesday, August 25, 2026

6:16 AM → 9:45 AM
3h 28m • 1 change
6:52 AM → 10:15 AM
3h 22m • 1 change
7:19 AM → 10:45 AM
3h 25m • 1 change
7:51 AM → 11:15 AM
3h 23m • 1 change
Show more

Departing Wednesday, August 26, 2026

6:16 AM → 9:45 AM
3h 28m • 1 change
6:52 AM → 10:15 AM
3h 22m • 1 change
7:19 AM → 10:45 AM
3h 25m • 1 change
7:51 AM → 11:15 AM
3h 23m • 1 change
Show more

Departing Thursday, August 27, 2026

6:16 AM → 9:45 AM
3h 28m • 1 change
6:52 AM → 10:15 AM
3h 22m • 1 change
7:19 AM → 10:45 AM
3h 25m • 1 change
7:51 AM → 11:15 AM
3h 23m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Roma Ostiense to Milano Centrale Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.