Roma Ostiense to Siena Trains

Roma Ostiense to Siena trains

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Trip Overview

The average train between Roma Ostiense and Siena takes 4h 2m and the fastest train takes 3h 25m. There is a train service every few hours from Roma Ostiense to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 2m
Duration: 358 km
Distance: €50
Average price: Hourly
Frequency

Train

best

Take the train from Roma Termini to Firenze S.M.N.train Fr
Take the train from Firenze S.M.N. to Sienatrain Re

4h 29m

€40–82

Roma Ostiense to Siena train times

Trains run hourly between Roma Ostiense and Siena. The earliest departure is at 5:49 AM in the morning, and the last departure from Roma Ostiense is at 9:34 PM which arrives into Siena at 7:55 AM. All services require a transfer at Piramide and take an average of 4h 2m. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

10:10 AM → 1:40 PM
3h 29m • 2 changes
11:58 AM → 3:37 PM
3h 38m • 2 changes
3:12 PM → 6:40 PM
3h 27m • 2 changes
3:57 PM → 7:38 PM
3h 40m • 2 changes
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Departing Monday, November 2, 2026

5:49 AM → 9:38 AM
3h 48m • 2 changes
7:10 AM → 10:40 AM
3h 29m • 2 changes
7:55 AM → 11:40 AM
3h 44m • 2 changes
9:12 AM → 12:38 PM
3h 25m • 2 changes
Show more

Departing Tuesday, November 3, 2026

5:49 AM → 9:38 AM
3h 48m • 2 changes
7:10 AM → 10:40 AM
3h 29m • 2 changes
7:55 AM → 11:40 AM
3h 44m • 2 changes
9:12 AM → 12:38 PM
3h 25m • 2 changes
Show more

Departing Wednesday, November 4, 2026

5:49 AM → 9:38 AM
3h 48m • 2 changes
7:10 AM → 10:40 AM
3h 29m • 2 changes
7:55 AM → 11:40 AM
3h 44m • 2 changes
9:12 AM → 12:38 PM
3h 25m • 2 changes
Show more

Departing Thursday, November 5, 2026

5:49 AM → 9:38 AM
3h 48m • 2 changes
7:10 AM → 10:40 AM
3h 29m • 2 changes
7:55 AM → 11:40 AM
3h 44m • 2 changes
9:12 AM → 12:38 PM
3h 25m • 2 changes
Show more

Departing Friday, November 6, 2026

5:49 AM → 9:38 AM
3h 48m • 2 changes
7:10 AM → 10:40 AM
3h 29m • 2 changes
7:55 AM → 11:40 AM
3h 44m • 2 changes
9:12 AM → 12:38 PM
3h 25m • 2 changes
Show more

Departing Saturday, November 7, 2026

5:49 AM → 9:38 AM
3h 48m • 2 changes
7:10 AM → 10:40 AM
3h 29m • 2 changes
7:55 AM → 11:40 AM
3h 44m • 2 changes
9:12 AM → 12:38 PM
3h 25m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Roma Ostiense to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.