The average train between Roma Termini and San Donato Milanese takes 4h 46m and the fastest train takes 4h 14m. There is a train service every few hours from Roma Termini to San Donato Milanese. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Roma Termini and San Donato Milanese. The earliest departure is at 5:35 AM in the morning, and the last departure from Roma Termini is at 7:40 PM which arrives into San Donato Milanese at 5:39 AM. All services require a transfer, and take on average 4h 46m. The schedules shown below are for the next available departures.

4h 34m • 1 change

4h 24m • 1 change

4h 44m • 1 change

4h 24m • 1 change

4h 34m • 1 change

4h 24m • 1 change

4h 44m • 1 change

4h 24m • 1 change

4h 34m • 1 change

4h 24m • 1 change

4h 44m • 1 change

4h 24m • 1 change
Want to know about travelling from Roma Termini to San Donato Milanese? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Roma Termini to San Donato Milanese. However, there are services departing from Roma Termini station and arriving at San Donato Milanese station via Milano Rogoredo. The journey, including transfers, takes approximately 4h 46m.
Roma Termini to San Donato Milanese train services, operated by Trenitalia Frecce, depart from Roma Termini station.
Roma Termini to San Donato Milanese train services, operated by Trenitalia Frecce, arrive at Milano Rogoredo station.
The distance between Roma Termini and San Donato Milanese is 468.9 km. The road distance is 559 km.
Trenitalia Frecce operates a train from Roma Termini to Milano Rogoredo every 30 minutes. Tickets cost €80–170 and the journey takes 3h 28m.