The average train between Roma Termini and Santo Stefano Ticino takes 3h 58m and the fastest train takes 3h 40m. There is a train service every few hours from Roma Termini to Santo Stefano Ticino. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Roma Termini and Santo Stefano Ticino. The earliest departure is at 5:40 AM in the morning, and the last departure from Roma Termini is at 8:05 PM which arrives into Santo Stefano Ticino at 11:50 PM. All services require a transfer at Milano Rogoredo and take an average of 3h 58m. The schedules shown below are for the next available departures.

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4h 7m • 1 changeWant to know about travelling from Roma Termini to Santo Stefano Ticino? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Roma Termini to Santo Stefano Ticino. However, there are services departing from Roma Termini station and arriving at Santo Stefano Ticino station via Milano Rogoredo. The journey, including transfers, takes approximately 3h 58m.
Roma Termini to Santo Stefano Ticino train services, operated by ItaloTreno, depart from Roma Termini station.
Roma Termini to Santo Stefano Ticino train services, operated by ItaloTreno, arrive at Milano Rogoredo station.
The distance between Roma Termini and Santo Stefano Ticino is 491.8 km. The road distance is 585 km.
ItaloTreno operates a train from Roma Termini to Milano Rogoredo hourly. Tickets cost €70–140 and the journey takes 2h 54m.